Immune-related adverse events in hepatitis treated with thiopurine-based immunosuppressants: A case reportCase Reports Published on 2023-05-012023-05-31 Journal: Thoracic cancer [Category] A형 간염, Fulltext, [키워드] azathioprine Hepatitis immune-related events mercaptopurine. [DOI] 10.1111/1759-7714.14859 PMC 바로가기 [Article Type] Case Reports
Accelerated waning of immunity to SARS-CoV-2 mRNA vaccines in patients with immune-mediated inflammatory diseases면역 매개 염증성 질환 환자에서 SARS-CoV-2 mRNA 백신에 대한 면역 약화 가속화Observational Study Published on 2022-06-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, [키워드] Adaptive immunity Adult patients All participants ankylosing spondylitis anti-TNF Arthritis attrition Autoimmune diseases azathioprine COVID-19 COVID-19 vaccination declining disease donation dose Efficacy examined force greater healthy control healthy controls Immune-mediated inflammatory disease Immune-mediated inflammatory diseases Immunity immunogenicity immunology Immunosuppressant immunosuppressants immunosuppressive therapies Immunotherapy immunotherapy. Inflammatory bowel disease Inflammatory diseases information Juan methotrexate mRNA vaccine neutralization Observational cohort study omicron Participants Patient rapid response rheumatoid arthritis SARS-CoV-2 SARS-CoV-2 variants Speck spondylitis subjects Support T cell T cell response Task Force Treatment undetectable Vaccine variants variants of concern [DOI] 10.1172/jci.insight.159721 PMC 바로가기 [Article Type] Observational Study
Humoral response to SARS-CoV-2 infection and vaccines against COVID-19 in patients with neuromyelitis optica spectrum disorders: Impact of immunosuppressive treatment시신경척수염 스펙트럼 장애 환자의 SARS-CoV-2 감염 및 코로나19 백신에 대한 체액 반응: 면역억제 치료의 영향Article Published on 2022-06-012022-09-11 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] antibody azathioprine B-cell Belgrade Complete COVID-19 COVID-19 in patient depleting disease ELISA evaluate humoral Humoral response IgG Immunosuppressive treatment Impact inebilizumab Infection mycophenolate NMOSD occurred Patient patients patients treated patients with COVID-19 Receptor binding domain SARS-CoV-2 IgG SARS-COV-2 infection sequence Seroconversion seroconverted serum IgG Spike protein the SARS-CoV-2 the spike protein treated vaccination vaccination. Vaccine was impaired was measured [DOI] 10.1016/j.msard.2022.103794 PMC 바로가기 [Article Type] Article
SARS-CoV-2 (COVID-19) pneumonia patient treated with two doses of infliximab within 2 weeks for acute severe ulcerative colitis A case reportSARS-CoV-2(COVID-19) 폐렴 환자, 급성 중증 궤양성 대장염 2주 이내 인플릭시맙 2회 투여 증례 보고Case Reports Published on 2022-01-282022-09-12 Journal: Medicine [Category] 진단, [키워드] abdominal pain acute COVID-19 acute respiratory syndrome Administered an infectious disease caused by the SARS-CoV-2 virus anti-TNF anti-TNF-α azathioprine bleeding bloody can be used Case report caused Clostridium difficile Colitis Colon complications coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 infection COVID-19 patient COVID-19 symptom COVID-19 symptoms current cytomegalovirus deteriorate diagnosed diagnosis of COVID-19 diarrhea dose Fever Immune-mediated inflammatory diseases Immunosuppressant immunosuppressants Immunotherapy IMPROVE induce Infection Infectious disease Inflammatory diseases infliximab inhibitor intravenous Loading dose male mesalamine Nasopharyngeal swab Necrosis necrosis factor antagonists nine outcomes pandemic Patient Pneumonia positive receiving Remission Research SARS-CoV-2 SARS-CoV-2 virus Severe acute respiratory syndrome Sigmoidoscopy spontaneous bleeding surgery tested the SARS-CoV-2 virus therapy treated Treatment Tumor tumor necrosis tumor necrosis factor ulcerative colitis [DOI] 10.1097/MD.0000000000028722 PMC 바로가기 [Article Type] Case Reports
Immunogenicity of BNT162b2 Vaccine in Patients with Inflammatory Bowel Disease on Infliximab Combination Therapy: A Multicenter Prospective StudyArticle Published on 2021-11-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age antibody azathioprine BNT162b2 clinical trial Combination combination therapy Concentration control group COVID-19 COVID-19 vaccination COVID-19 vaccine dose evaluate excluded group healthy IBD IgA IgA level IgA levels IgG immunogenicity Inflammatory bowel disease infliximab IQR median mRNA vaccine multicenter neutralizing antibody of BNT162b2 outcomes participant Participants Patient patients treated percentage positive Primary outcome Prospective Prospective Study PROTECT receiving recruited SARS-CoV-2 antibody SARS-CoV2 seroconverted Serologic response Sex significantly lower study group the study group the vaccine vaccination Vaccine [DOI] 10.3390/jcm10225362 PMC 바로가기 [Article Type] Article
Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19면역매개염증질환 및 코로나19 환자에서 종양괴사인자억제제와 입원 또는 사망 위험 간의 연관성Research Published on 2021-10-182022-09-12 Journal: JAMA Network Open [Category] MERS, SARS, 진단, [키워드] 6-mercaptopurine 95% CI accounted accounting Adult patients age analysis Analysis Arthritis association azathioprine category Clinical characteristics cohort study Combination conducted correlations country COVID-19 COVID-19 diagnosis Crohn disease data entry death demographic and clinical characteristics diagnose Diagnosis died Europe excluded exposure Factor female finding higher odd higher odds Hospitalization Hospitalized immune pathway Immune-mediated inflammatory disease Immune-mediated inflammatory diseases immunomodulatory Importance individual Inflammatory arthritis Inflammatory bowel disease Inflammatory diseases inhibitor International Janus kinase Kinase inhibitor lower risk measure methotrexate monotherapy multivariable logistic regression Necrosis objective Odds ratio outcome pandemic participant Patient Point psoriasis receipt receiving reference treatment Relevance reported reporting bias Result Rheumatic diseases rheumatoid arthritis risk Sensitivity analyses sensitivity analysis setting significantly higher Support Symptom the mean therapy TNF treatment regimen Tumor tumor necrosis tumor necrosis factor [DOI] 10.1001/jamanetworkopen.2021.29639 PMC 바로가기 [Article Type] Research
Risk of COVID-19 and its complications in patients with atopic dermatitis undergoing dupilumab treatment—a population-based cohort study두필루맙 치료를 받는 아토피 피부염 환자의 코로나19 위험 및 합병증 - 인구 기반 코호트 연구Original Article Published on 2021-10-132022-09-12 Journal: Immunologic research [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI AD atopic dermatitis azathioprine biologics comparable Complication complications conducted coronavirus disease Corticosteroids COVID-19 COVID-19 complication COVID-19 complications Dupilumab elevated Hospitalization incidence of COVID-19 incidence rate increased risk Infection Mortality mycophenolate mycophenolate mofetil pandemic Patient patients treated phototherapy population-based cohort risk Safe SARS-COV-2 infection systemic corticosteroid treated [DOI] 10.1007/s12026-021-09234-z PMC 바로가기 [Article Type] Original Article
Myasthenia gravis associated with anti-MuSK antibodies developed after SARS-CoV-2 infectionSARS-CoV-2 감염 후 개발된 항-MuSK 항체와 관련된 중증 근무력증Case Reports Published on 2021-10-012022-09-11 Journal: European journal of neurology [Category] MERS, SARS, 진단, 치료기술, [키워드] Acetylcholine acetylcholine receptor affecting anti-MuSK antibodies antibodies antibody Autoimmune diseases azathioprine CBA cell-based assay Central nervous system clinical response Coronavirus infection correlation described Diagnosis eight element followed by immunohistochemistry immunosuppressive immunosuppressive therapy Infection low-density Low-density lipoprotein mechanism musk myasthenia gravis myasthenia gravis. nervous system Neurological complication Neurological complications neuromuscular junction Novel coronavirus pandemic Patient performed Peripheral nervous system Protein pyridostigmine radioimmunoassay receptor reported RIA SARS-CoV-2 SARS-COV-2 infection secondary to serological serum antibodies serum antibody Symptom the disease the timing therapy treated Treatment Trigger tyrosine viral disease Viral diseases [DOI] 10.1111/ene.14721 PMC 바로가기 [Article Type] Case Reports
A rare case of Polyarteritis Nodosa associated with autoimmune hepatitis: a case reportCase Report Published on 2021-05-262023-08-28 Journal: BMC Rheumatology [Category] E형 간염, [키워드] Autoimmune hepatitis azathioprine Cyclophosphamide polyarteritis nodosa [DOI] 10.1186/s41927-021-00188-1 PMC 바로가기 [Article Type] Case Report
COVID-19 and IBD drugs: should we change anything at the moment?Comment Published on 2021-04-012023-07-11 Journal: Gut [Category] SARS, [키워드] azathioprine COVID-19 Crohn's disease Inflammatory bowel disease infliximab. [DOI] 10.1136/gutjnl-2020-323247 PMC 바로가기 [Article Type] Comment